Three Independent, Double Blind Studies

Skin Rejuvenation Regimens
Published March/April, 2003 Archives of Plastic Surgery
Treatment used in study: High Potency Serum

In a 10-week independent study examining the effects of skin rejuvenation regimens treating photodamaged skin, Dr. John Rachel and Dr. Jasmin Jamora found “significant changes are noted when combining topical treatment with superficial peels.”  Topical treatment used in study was Cellex-C’s High Potency Serum.

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Topical Vitamin C Preparation Reduces Erythema of Rosacea
Published February, 2001 Cosmetic Dermatology
Treatment used in study: Eye Contour Cream

The study by Dr R.B. Carlin examining the therapeutics effects of topical vitamin C on patients with acne rosacea revealed that a variation of Cellex-C’s patented ingredient complex “produced clinically and statistically significant results in reducing erythema within 3 weeks.”  Additionally, the study also states that “although vitamin C is quantitatively the principle ingredient (not counting water), we cannot rule out therapeutic contributions from other ingredients in apparent “trace” quantities (e.g., zinc, tyrosine and vitamin E, the exact concentrations of which are proprietary secrets). Therefore, conclusions about efficacy in our study are more precisely assigned to the whole product rather than solely to vitamin C.”

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Use of Topical Vitamin C and its Effects on Photodamaged Skin Topography
Published October, 1999 Archives of Otolaryngology
Treatment used in study: High Potency Serum

A double blind, independent study conducted by Dr. Stephen Traikovich consisting of 3 months’ use of topical vitamin C in a daily regime “showed a topographic improvement in facial photodamaged skin using Cellex-C.”  Additionally, the study also states that “it should also be mentioned that there are an increased number of vitamin C based topical cosmetics available on the market. It appears that not all preparations of vitamin C are effective.  Many of these products utilize derivatives, esters and analogs of vitamin C that are either unable to penetrate into the skin, unable to be chemically converted to L-ascorbic acid (the only form that can be utilized by the body), and/or unable to be delivered in adequate concentration to have an effect.  These ascorbic acid substitutes include ascorbyl palmitate, magnesium ascorbyl palmitate, ascorbic acid magnesium phosphate, which are easily stabilized but must be converted to L-ascorbate to be effectively useful. There is no direct evidence that ascorbic acid derivatives enter the skin in appreciable amounts, and it appears that their conversion to L-ascorbic acid is largely inefficient, therefore, precluding effective concentration delivery.”

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